Chronic lymphocytic leukemia patients clustered into groups by their heatshock proteins and phosphoprotein levels. Heatmap shows protein expression data from 871 peripheral blood patient samples relative to expression in 5 normal CD19+ samples.

Outcome Curves

Overall Survival Time to First Treatment Time to Second Treatment
All BTKi Chemo
os_fav os_unf os_tot efs_tot cr_tot os_int efs_int cr_int efs_fav cr_fav cr_int

Functional Protein Expression Patterns

Protein cluster 1
Protein cluster 2
Protein cluster 3
Protein cluster 4