Acute myeloid leukemia patients clustered into groups by their global proteins and phosphoprotein levels. Heatmap shows data from fresh bone marrow and peripheral blood samples.

Survival Curves

Overall Survival Complete Remission
All Intermediate Favorable Unfavorable
os_fav os_unf os_tot cr_tot os_all_DNMT3Amt os_all_DNMT3Awt cr_all_DNMT3Amt cr_all_DNMT3Awt os_all_IDH1mt cr_all_IDH1mt os_all_IDH1wt cr_all_IDH1wt os_all_IDH2mt cr_all_IDH2mt os_all_IDH2wt cr_all_IDH2wt os_all_N-MUT&F-MUT cr_all_N-MUT&F-MUT os_all_N-MUT&F-WT cr_all_N-MUT&F-WT os_all_N-WT&F-MUT cr_all_N-WT&F-MUT os_all_N-WT&F-WT cr_all_N-WT&F-WT os_int cr_int os_int_DNMT3Amt cr_int_DNMT3Amt os_int_DNMT3Awt cr_int_DNMT3Awt os_int_flt3mt cr_int_flt3mt os_int_flt3wt cr_int_flt3wt os_int_IDH1mt cr_int_IDH1mt os_int_IDH1wt cr_int_IDH1wt os_int_IDH2mt cr_int_IDH2mt os_int_IDH2wt cr_int_IDH2wt os_int_npm1mt cr_int_npm1mt os_int_npm1wt cr_int_npm1wt cr_fav cr_unf

Signature-based Drug Targets

Upregulated Downregulated


up1 up2 up3 up4 up5 up6 up7 up8 up9 up10 up11 up12 up13 down1 down2 down3 down4 down5 down6 down7 down8 down9 down10 down11 down12 down13