DNA Damage

Heatmap

heatmap

Pediatric acute myeloid leukemia patients clustered into groups by their dna_damage proteins and phosphoprotein levels. Heatmap shows protein expression data from 500 peripheral blood patient samples relative to expression in 30 normal CD34+ samples.

Outcome Curves

Overall Survival Event-Free Survival Complete Remission
All ADE ADEB
os_fav os_unf os_tot efs_tot cr_tot os_all_DNMT3Amt os_all_DNMT3Awt cr_all_DNMT3Amt cr_all_DNMT3Awt efs_all_DNMT3Amt efs_all_DNMT3Awt os_all_IDH1mt cr_all_IDH1mt efs_all_IDH1mt os_all_IDH1wt cr_all_IDH1wt efs_all_IDH1wt os_int efs_int cr_int efs_fav cr_fav cr_int

Functional Protein Expression Patterns

Protein cluster 1
Protein cluster 2
Protein cluster 3
Protein cluster 4